proceeding

Saccharomyces cerevisiae asosida SARS-CoV-2 S1 rekombinant oqsilini olish texnologiyasini o‘rganish

Toshboyeva Fotima Nuriddin qiziMirzo Ulug‘bek nomidagi O‘zbekiston Milliy universitetiAyubov M.S.O‘zbekiston Respublikasi Fanlar akademiyasi Genomika va bioinformatika markaziRavshanov Hamroqul To‘ymurod o‘g‘liMirzo Ulug‘bek nomidagi O‘zbekiston Milliy universiteti

2026en

Ochiq kirishOltin

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Annotatsiya

This article examines the use of Saccharomyces cerevisiae as an expression system for producing a recombinant SARS-CoV-2 antigen within a subunit vaccine development platform. The study focuses on the pYES2-S1-Zeo construct intended for expression of the SARS-CoV-2 S1 protein in yeast cells. According to the dissertation materials, S. cerevisiae was isolated from baker’s yeast, culture purity was checked microscopically, and a recombinant expression approach was applied. SDS-PAGE and Western blotting were selected for evaluation of recombinant protein expression, with a predicted molecular mass of 61 kDa for S1. The available materials support the study of S. cerevisiae as a recombinant antigen expression platform.

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Identifikatorlar

DOI: 10.66073/refocus-conf/3010041

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