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[Experimental study of pharmacotherapeutic effect of phytoecdisteroids and nerobol in toxic liver damage].

В. Н. СыровInstitute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, ul. Kh. Abdulaeva 77, Tashkent, 700170 UzbekistanЗ. А. Хушбактова
PubMedrepository2001en
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Annotatsiya

Phytoecdysteroids ecdysteron and turkesteron isolated from Ajuga turkestanica (Rgl.) Brig. decrease the manifestations of uremic intoxication in rats with experimental renal pathology induced by a nephrotoxic mixture (containing uranyl acetate and glycerol). Injected in a dose of 5 mg/kg, the drugs restore glomerular filtration level, favor the disappearance of the albuminuria and normalize urinary sediments. The nephroprotector effect of the phytoecdysteroids studied resembles the action of a steroidal anabolic drug nerobol.

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