[Immunomodulating effect of the novel water-soluble gossypol derivative Mebavin in adjuvant arthritis].
Sabirova FmDepartment of Experimental Medicine and Pathologic Anatomy, State Center of Emergency Medicine, ul. Farhod 2, Tashkent, 700107 UzbekistanUrazmetovaMadaminov Aa
ABI
Annotatsiya
Investigation of the effect of mebavin on the model of adjuvant arthritis showed that this drug administered in a dose of 100 mg/kg exhibits immunomodulant and anti-inflammatory activity without negative influence on the nonspecific response of the organism. Combined administration of mebavin with prednisolone provides for a more effective and nontoxic treatment of adjuvant arthritis.
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