Internal organ lesions in patients with acute leukemia according to autopsy data
Элдор ИсхаковDSc, Associate professor, Head of Department of «Hematology and Transfusiology», Tashkent State Institute of Postgraduate Medical Education, Ministry of Health of the Republic of UzbekistanХасан ТурсуновDSc, professor, Head of Department of Pathological Anatomy, Tashkent Medical Academy, Ministry of Health of the Republic of Uzbekistan, Tashkent, UzbekistanSaidjalol BakhramovDSc, professor, Department of Hematology and Transfusiology, Tashkent State Institute of Postgraduate Medical Education, Ministry of Health of the Republic of Uzbekistan, Tashkent, Uzbekistan
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The analysis of the condition of the internal organs in 17 patients with acute leukemia who died before treatment and at various stages of the antitumor cytostatic treatment was performed. In those cases when patients died before the start of cytostatic treatment, almost all internal organs had a specific lesion of blast cells, which was the cause of death in these patients. In patients who died in a state of myelotoxic aplasia of hematopoiesis, the cause of death was gross dystrophic changes in the internal organs, which led to multiple organ failure due to resistant sepsis.
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