ASSESSMENT OF THE STATE OF THE HYPOTOLAMO-HYPOPHYSICAL SYSTEM IN EPILEPSY

At the present stage, epilepsy refers to neuropsychiatric diseases, which, according to the WHO definition, require considerable attention, since the frequency of this disease tends to increase every year. The paper analyzes the features of clinical manifestations of imbalance in the functioning of the hypothalamic-pituitary system in patients with epilepsy. In the scientific work, 103 patients with epilepsy were examined, including 57 patients with epilepsy (group 1), 46 patients with epilepsy and signs of hypothalamic-pituitary syndrome (HHS; group 2). It has been proven that functional restructuring of the state of the brain in patients with epilepsy significantly alters the activity of the hypothalamic-pituitary system. This is confirmed by the identified autonomic disorders, changes in the bioelectrical activity of the brain, disorders in the hypothalamus-pituitary-thyroid gland and hypothalamus-pituitary-adrenal glands, disruption of the integrated connections between these systems.

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