POLYORGAN INSUFFICIENCY DURING OBTURATION OF GALLERY IN THE EXPERIMENT

Reologic condition of the blood in white female rats with obturation of bile ducts, as well as microcirculation of the liver, small intestine, and kidneys, the process of free radicals.\n\n\nThe remarkable change in reologic blood features as hyperviscosity and blood flow decrease has been revealed.\n\n\nChanges in microcirculation are observed both in the intestine and in the kidneys and liver. In kidneys, they are more marked. In obturation of bile ducts, the intense free radicals oxidation along with the decrease of antioxidant enzymes activity, particularly superoxide dismutase (SOD) is observed.\n\n\nThese changes indicate the involvement of the liver, small intestine, and kidneys in the pathology of the development of multiple organ failure during obstruction of the bile ducts

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