Comparison of 18F-MFBG and 68Ga-DOTATATE PET/CT in the Imaging of Metastatic Paraganglioma and Pheochromocytoma
Maoxue DengDepartment of Nuclear Medicine, The Affiliated Hospital of Southwest Medical UniversityQiaoqiao ShuDepartment of Nuclear Medicine, The Affiliated Hospital of Southwest Medical UniversityMei HuSchool of Pharmacy, Southwest Medical University, Luzhou, Sichuan, ChinaYue ChenDepartment of Nuclear Medicine, The Affiliated Hospital of Southwest Medical UniversityLiang CaiDepartment of Nuclear Medicine, The Affiliated Hospital of Southwest Medical University
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ABSTRACT: Two men with metastatic paraganglioma/pheochromocytoma underwent PET/CT examination in our hospital to understand the treatment effect and progression of the disease. Both patients had previously been treated with 131 I-MIBG, and at this evaluation, both of them underwent 68 Ga-DOTATATE and 18 F-MFBG PET/CT. The 68 Ga-DOTATATE PET/CT showed more metastases in the images of these 2 patients. This case highlighted that 68 Ga-DOTATATE PET/CT is superior to 18 F-MFBG PET/CT in detecting metastases from paraganglioma and pheochromocytoma in these 2 patients.
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