Distribution of congenital anomals in children, risk factors

In world congenital anomalies are serious medical and social problem. They doubled over last decade 20th century and played significant role in the structure pathology and mortality in the infant, perinatal and children. Now time is 1800 out of 10,000 children born with congenital anomalies. Through progress made in our country in the future reform health system strengthening and the protection of the health children, congenital abnormalities play leading role in the structure morbidity disability and mortality. Reasons development of 40-60% anomalies is unknown. Apply the term "sporadic the defect of birth", meaning unknown cause, accidental appearance and low risk re appearance have future children. For 20-25% of anomalies more likely "multi-factor" reason - complex interaction many small genetic defects and risk factors environmental environment. The rest 10-13% of anomalies associated with the influence environment. Only 12-25% of anomalies have purely genetic causes (Akhmadalieva et al., 2020). Statistics shows disproportionate a high proportion of the total number survivors newborns premature children who suffer physical, intellectual and emotional disability.

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