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The role of VEGF-A gene polymorphism in development and progression of PDR in men of Uzbek population with type 2 diabetes

Akramova G.The Republican Specialized Scientific and Practical Medical Center of Endocrinology, Ministry of Health of the Republic of UzbekistanAlikhanova N.MThe Republican Specialized Scientific and Practical Medical Center of Endocrinology, Ministry of Health of the Republic of UzbekistanTakhirova F.AThe Republican Specialized Scientific and Practical Medical Center of Endocrinology, Ministry of Health of the Republic of UzbekistanAbboskhudjaeva L.SThe Republican Specialized Scientific and Practical Medical Center of Endocrinology, Ministry of Health of the Republic of UzbekistanShakirova M.MThe Republican Specialized Scientific and Practical Medical Center of Endocrinology, Ministry of Health of the Republic of Uzbekistan
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The research has shown that C634G polymorphism of the VEGF-A gene is associated with duration of the disease, presence of hypertension, level of blood pressure in the morning and in the evening =130 mmHg, TG= 1.7 mmol/l and LDL =2.5 mmol/l. Consequently, C634G polymorphism of the VEGF-A gene is one of the factors for predicting the risk of proliferative diabetic retinopathy in men with type 2 diabetes in Uzbek population.

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