Biochemical markers of preeclampsia development and criteria for early diagnosis

Abstract It has been proved that the amount of sFlt-1 in the blood serum of pregnant women with the risk of developing early and late preeclampsia increases rapidly, the amount of PlGF decreases, and the ratio of sFlt-1/PlGF increases progressively. If the sFlt-1/PlGF ratio is higher than 28 in the 1st trimester of pregnancy, there is a high risk of developing early PE, if it is higher than 57-60 in the 2nd trimester, PE may develop, and if it is higher than 80-100, it can predict the development of severe preeclampsia.

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