FEATURES OF THE INCIDENCE OF POSTOPERATIVE COMPLICATIONS IN PATIENTS WITH TRANSSPHENOIDAL PITUITARYADENOECTOMY

Patients were distributed as follows: depending on the hormonal activity of patients with adrenocorticotropic hormone secreting Cushing's syndrome-60, аcromegaly-60, inactive pituitary adenoma-60; depending on the size of the formation: 93 (51.6%) were with macroadenomas, 87 (48.3% ) with pituitary microadenomas. An analysis of the incidence of postoperative complications in the short term (1 month) revealed that in 81 (45%) patients with hypopituitarism; hypothyroidism in (70)39%; hypogonadism in 50(28%); diabetes insipidus in 7(4%); transient diabetes insipidus in 11(6%); visual acuity deterioration in 2 (1.2%) patients and liquorrhea in 3 (5.4%) patients. At the same time, there was a normalization of elevated hormone levels in 133 (74%) patients; 30% improvement in vision; lack of disease dynamics in 47 (26%). Despite the persistent phenomena of hypopituitarism 47(26%) and diabetes insipidus 11(6%), which were mainly observed in 165(92%) patients with macroadenomas and did not depend on the organ activity of the formation (against 54(30%) cases with microadenomas) .In the long-term follow-up of patients after TРА (t 3 months to 1 year), an improvement in pituitary function was noted in the form of restoration of gonadotropic insufficiency, phenomena of transient diabetes insipidus and improvement in hypertensive cephalgia.

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