MORPHOLOGICAL CHANGES OF BRONCH AND LUNG PARENCHYMA IN PNEUMOPATHIES DEPENDING ON GESTATION DATE

Objective: To determine the nature of pathomorphological changes in the bronchial wall and lung tissue of newborns who died from various forms of pneumopathy, depending on the gestational age. Methods: The study includes materials from the corpses of 74 newborns who died in the perinatal center of the Samarkand region from various forms of pneumopathy, whose bodies were subjected to an autopsy study in the pathoanatomical department of the Samarkand regional multidisciplinary hospital. Results: Depending on the specific nosological forms of pneumopathy in newborns, based on their periods of maturity, the material was divided into the following groups: 1) Primary lung atelectasis by gestation: 22-28 weeks, 29-31 weeks and 32-37 weeks. 2) Hyaline membrane disease depending on the life expectancy of infants. 3) Pneumopathy with edematous-hemorrhagic form of pathology, also based on the timing of neonatal life. An autopsy study of the lungs of infants with a primary diagnosis of primary pulmonary atelectasis revealed macroscopically airless, cyanotic, dormant lungs with a reduced volume and pointed, flat edges that did not completely fill the volume of the pleural cavities. Conclusions: Thus, the main morphological forms of pneumopathy in premature newborns are primary atelectasis and hyaline membrane disease.

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