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VERNONIA ANTHELMINTICA BARGIDAN AJRATILGAN THERMOTHELOMYCES THERMOPHILES XJF-9 ENDOFIT ZAMBURUG`INING KUCHLI BIOLOGIK FAOLLIGI

Nigora RustamovaKahramon Davranovich DavranovHaji Akber AisaAbulimiti Yili

Journal of Chemistry of Goods and Traditional Medicinejournal2022uz

ABI

Annotatsiya

Endofitik mikroorganizmlar tomonidan ishlab chiqarilgan ikkilamchi metabolitlar yangi dorilarni kashf qilish uchun biologik faol birikmalarning muhim boy manbaidir. Ushbu tadqiqotda ilk bor Vernonia anthelmintica o`simligining bargidan endofitik zamburug`ning ajratib olinishi, 18S rRNK gen ketma-ketligi usuli bilan identifikatsiya qilininshi hamda endofit zamburug` tomonida ishlab chiqarilgan ikkilamchi mitabolitlarning farmakologik faolligiga asoslangan. Thermothelomyces thermophiles XJF-9 zamburug'li shtammi Staphylococcus aureus, Escherichia coli bakteriya va Candida albicans zamburug` patogenlariga qarshi ko'rsatishda istiqbolli natijalarni ko'rsatdi. Bundan tashqari, sitotoksik va diabetga qarshi faollik ham namayon etdi.

Mavzular

Microbial Natural Products and Biosynthesis Enzyme Production and Characterization Biochemical and Structural Characterization

Identifikatorlar

DOI: 10.55475/jcgtm/vol1.iss4.2022.77

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