CLINICAL AND IMMUNOLOGICAL FEATURES OF BRONCHOOSTRUCTIVE SYNDROME IN CHILDREN OF EARLY AND PRESCHOOL AGE

<em>At present, all over the world, the study of the phenotypes of bronchial obstruction in children of early and preschool age remains a subject of great scientific interest. The identification of phenotypes is necessary for a better understanding of the etiopathophysiological, including epigenetic, mechanisms of the disease, the determination of predictors and the prediction of the risk of BA. In this regard, the aim of the study was to study the clinical and immunological features of broncho-obstructive syndrome in children of early and preschool age. On the basis of the SF of RSCEMA, 111 patients aged from 1 to 6 years were examined. The results of the study showed that under conditions of prolonged antigenic load, humoral immunity is activated; children with RSMS have hyperimmunoglobulinemia G and M, which is the cause of incomplete immunity. </em>

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