THE ROLE OF THE IMMUNE SYSTEM AND ORAL FLUID AND BLOOD ANTIMICROBIAL PEPTIDES IN PATIENTS WITH CHRONIC GENERALIZED PERIODONTITIS

Immunological mechanisms play the leading role in the pathogenesis of inflammatory destructive processes in periodontium. That's why clinical manifestations of chronic generalized periodontitis depend not so much on pathogenicity and virulence of corresponding microflora but on the character of bacterial-gostal interrelations, that is, in many respects - on the degree of macroorganism reactivity, which is determined by the functional state of immune system. Consequently, an important step in understanding the nature of inflammatory periodontal diseases is the study of those immunological factors (cytokines and antibodies) as well as enzymes that can cause shifts in the morpho-functional state of the supporting apparatus of the tooth, as well as cause the corresponding clinic of the indicated pathology.

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