A clinical case of pityriasis rubra pilaris - juvenile type
Bahrambek MukhamedovDepartment of Therapeutic Subjects, Tashkent State Dental Institute, Tashkent, UzbekistanEvelina KoldarovaDermatology Department, Asmo clinic, Tashkent, UzbekistanObid KurbanovDepartment of Therapeutic Subjects, Tashkent State Dental Institute, Tashkent, Uzbekistan
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Pityriasis rubra pilaris is a rare chronic inflammatory papulo-squamous skin disease, the pathogenesis of which is still unclear. The pathological essence of the disease is associated with a violation of keratinization against the background of hyperactivity of keratinocytes with subsequent inflammation, as well as with vitamin A dysmetabolism and a weakening of the protein-binding fiction of the liver. Unfortunately, treatment is complex with inconsistent improvement from topical therapies, including emollients, keratolytics, corticosteroids, vitamin D analogs, and retinoids. We present a clinical case of the juvenile type of Devergie’s disease in a 3-year-old child, which was caused by poisoning.
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