PATHOGENETIC ASPECTS OF CHRONIC HEART FAILURE WITH PRESERVED EJECTION FRACTION

Chronic heart failure (CHF), being an outcome of cardiovascular continuum, leads to worsening of the course not only of the disease cause, but also to its decompensation, rehospitalizations, which leads to difficulties in care of these patients and becomes a socio-economic problem [1,2,11]. The prevalence of CHF in Western countries ranges from 1% to 2% in the general population, reaching 10% in those over 70 years of age [2,38]. Data from the EPOHA study, show an incidence of CHF of 7-10% in the Russian Federation [2,11]. In Uzbekistan, CHF is also one of the leading complications of cardiovascular disease (CVD) [1,13].

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