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Evaluation of the safety and acute toxicity of strains of the medicinal <i>Schizophyllum commune fr.</i> fungus

Jamila SherqulovaKarshi State Universty, Karshi, Republic of UzbekistanErkin EshonkulovKarshi State Universty, Karshi, Republic of UzbekistanXumoyun Qo‘ziboevKarshi State Universty, Karshi, Republic of Uzbekistan
BIO Web of Conferencesjournal2024en
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In this article, the safety grading of local strains JE4, JE5 and JE6 of the medicinal fungus S. commune and the study of the effect of acute toxicity in laboratory conditions are analyzed. The mycelial liquid of the strains was given to white mice in the same amount in the mouth, vein, and abdominal cavity. Experimental tasts were observed for 14 days. Permanent signs of dangerous toxicity in animals: changes in the color of the skin, fur, eyes and mucous membranes, activity towards food, behavior, changes in height, movement, sleep, tremors, seizures, salivation cases of separation, diarrhea and death were monitored. It is noted that the strains of Schizophyllum commune are harmless and not acutely toxic.

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Koʻrsatkichlar — AkademScholar · Tez orada