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Granular osteoconductive biopolymer and predictive analysis of its physical property changes in maxillofacial surgery

Denis G. AlekseevSamara State Medical University, Samara 443079, RussiaOleg V. SlesarevSamara State Medical University, Samara 443079, RussiaDarya V. MalchikovaSamara State Medical University, Samara 443079, RussiaVyacheslav G. BelanovSamara State Medical University, Samara 443079, RussiaNatalia A. MaksimenkoSamara State Medical University, Samara 443079, RussiaВ. И. ПлатоновSamara National Research University, Samara 443079, RussiaRavshanbek B. AbdullaevTashkent Medical Academy, Tashkent 100109, Uzbekistan

Computational and Structural Biotechnology Journaljournal2025en

ABI

Annotatsiya

) of the OGB fraction. Gas adsorption, Fourier transform infrared spectroscopy, and scanning electron microscopy substantiate that preoperative preparation methods enhance the physical property of the OGB fraction. These methods include the extraction of coarse and fine industrial dust from the granule surfaces and the removal of air pockets from the granule pores. Thus, studying OGB behavior in the recipient site justifies the use of prognostic indicators, which is clinically significant. These indicators enable the surgeon to design a 3D sculpture of the bioengineered scaffold structures, considering the changes in the physical property of the OGB fraction during the postoperative period. This approach minimizes the risks of postoperative complications caused by uncontrolled compaction of the OGB fraction. Preoperative preparation of the OGB fraction can significantly enhance its adsorption capacity, increasing it by up to 25 %.

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Mavzular

Bone Tissue Engineering Materials Facial Trauma and Fracture Management Orthodontics and Dentofacial Orthopedics

Identifikatorlar

DOI: 10.1016/j.csbj.2025.06.021

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