Comparative Characteristics of Immunocytochemistry Data in Groups of Patients with Macro- and Giant Non-Functional Pituitary Adenomas
Yu.М. UrmanovaAlfraganus University, Department of Internal Medicine, Republican Specialized Scientific and Practical Medical Center of Endocrinology named
after Academician E.Kh. Turakulov, Republic of Uzbekistan, 100190, Tashkent, Yunusabad district, st. Yukori Karakamysh, 2A, building C, floor
3, Uzbekistan
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We studied 20 patients with non-functional pituitary adenomas – NFPA- (Group 1 - 10 pituitary macroadenomas and Group 2 - 10 giant pituitary adenomas) who underwent transnasal pituitary adenomectomy. All patients underwent examinations, including examination of the fundus, measurement of visual fields every 3 months, studies of the levels of STH, IGF-1, LH FSH, ACTH, TSH, prolactin, free thyroxine, cortisol, as well as immunohistochemical studies of operated patients with determination of the levels of expression of Ki67, p53.
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