THE ROLE OF LAPAROSCOPIC SURGERY IN THE RECURRENCE OF CERVICAL CANCER
Annotatsiya
Resume. Objective of the Study: Based on multifactorial analysis, to evaluate the effectiveness, safety, and long-term outcomes (one-year mortality, overall survival, recurrence rate, localization, and time of recurrence) of minimally invasive and open radical hysterectomy in early-stage cervical cancer (CC). Materials and Methods: The study was conducted from 2010 to 2023 in the Oncology Gynecology Department of the Bukhara branch of RIO and RIATM. Inclusion criteria: (1) histologically confirmed cervical cancer, including all histological types; (2) stages IA1 - IIA2 (FIGO 2018); (3) extended hysterectomy (Type III) with pelvic and/or para-aortic lymphadenectomy as the primary surgical treatment. Patients with insufficient data were excluded. Depending on the surgical access, patients were divided into two groups: minimally invasive surgery and open surgery. Results: The analysis was conducted based on the following parameters: age, stage (FIGO 2018), substage by TNM, tumor histotype, tumor size, obstetric-gynecological history, comorbidities, primary treatment method, surgical access, tumor size, duration of surgery, blood loss volume, need for subsequent adjuvant therapy, intra- and postoperative complications. Additionally, long-term results were assessed in each group: overall survival and recurrence-free survival, one-year mortality. Conclusion: The results obtained in both groups were comparable, including overall and recurrence-free survival, indicating the safety and effectiveness of minimally invasive surgery compared to open surgery. Keywords: cervical cancer, laparoscopic surgery, recurrences, overall survival, open hysterectomy.