Frequency and risk assessment of obstructive sleep apnea in patients with chronic obstructive pulmonary disease
Annotatsiya
<bold>Objective:</bold> To assess the risks of obstructive sleep apnea (OSA) in patients with chronic obstructive pulmonary disease (COPD). <bold>Materials and methods:</bold> Screening was conducted on 223 COPD patients using the Berlin Questionnaire to identify categories such as: snoring and its characteristics; characteristics of wakefulness; elevated blood pressure or body mass index (BMI) of 30kg/m² or higher, indicative of high risk of sleep apnea. Outcomes: High prevalence of potential clinical markers of OSA - snoring (74%), "feeling of tiredness after sleep," "fatigue during wakefulness" (95.5%), "breath cessation during sleep" (91.5%) along with their diagnostically significant variations allowed interpreting the presence of high risk of sleep apnea in 64.1% of COPD patients, where predictive factors include age over 70 years (OR 2.44), BMI over 30 kg/m² (OR 4.67), neck circumference over 43 cm (OR 3.35), smoking intensity over 50 pack-years (OR 3.10), daily alcohol consumption (OR 2.9), sedative medication use (OR 1.47), comorbidity with ischemic heart disease (OR 2.11) and hypertension (OR 1.74), and the presence of severe obstructive disorders (OR 1.32). Among COPD patients with "excessive daytime sleepiness," the proportion of high-risk patients for sleep apnea is 95.2%. <bold>Conclusion:</bold> High risk of sleep apnea is observed in 64.6% of COPD patients and is associated with phenotypic multifactoriality, including gender, age, anthropometric parameters, smoking intensity, alcohol and sedative medication use, comorbidity with ischemic heart disease and hypertension.