MORPHOMETRIC CHANGES IN THE THYROID GLAND DURING CHEMICAL BURNS OF THE DIGESTIVE TRACT AND THEIR CORRECTION: AN ANALYTICAL APPROACH BASED ON LITERATURE REVIEW

Resume. Chemical injuries to the gastrointestinal (GI) tract from corrosive substances can cause extensive local damage and trigger widespread bodily reactions that impact remote organs like the thyroid gland. This review examines existing research on structural changes in the thyroid following such injuries, exploring underlying causes and possible ways to address them. We highlight how these burns vary from superficial irritation to deep tissue destruction, often leading to serious complications [1]. Key findings point to thyroid issues like distorted follicle shapes, immune cell buildup, and reduced hormone production, driven by inflammation, stress hormones, and disrupted signaling pathways. Diagnostic tools include tissue exams, hormone tests, and imaging. Treatments such as anti-inflammatories, antioxidants, and hormone supplements show promise, but more targeted options are lacking. Overall, recognizing and managing thyroid effects early could improve patient recovery, though additional studies are essential for better strategies. Keywords: Corrosive injury; gastrointestinal tract; thyroid structure; structural modifications; management approaches

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