COMPLEX COMPOUNDS OF CEFAZOLIN WITH METAL SALTS: MODERN CONCEPTS AND APPLICATION PROSPECTS.

The study of complex compounds of medicinal substances with metal ions is one ofthe most promising areas of modern bioorganics and pharmaceutical chemistry. Such compounds arecapable of changing the physico-chemical and pharmacological properties of starting preparations,increasing their resistance to hydrolysis and expanding the range of biological activity. The mechanismsof their formation, physico-chemical characteristics, biological activity and possible areas of practicalapplication are considered.

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