BETTA-PROPARGILOKSINAFTALINNI 2-BROM-4-NITROFENILAZID BILAN HALQALANISH REAKSIYASINI O'RGANISH
Annotatsiya
Beta-naftolni propargil bromid bilan alkillab tegishli 2-propargiloksinaftalin sintez qilingan. 2-brom-4-nitroanilindan diazotirlab natriy azid ta’sir ettirish orqali esa 2-brom-4-nitrofenilazid olingan. Sintez qilib olingan propargil efir va aromatik azidning o‘zaro siklobirikish reaksiyasi o‘rganilgan. Halqalanish natijasida 1H-1,2,3-triazolning 1,4-izomer hosilasi – 1-(2-brom-4-nitrofenil)-4-((naftalin-2-iloksi)metil)-1H-1,2,3-triazol hosil bo‘lishi aniqlangan. Reaksiyaga katalizator, harorat va erituvchilar ta’siri o‘rganilgan. Sintez qilingan moddalarning tuzilishi IQ, YaMR spektrlari orqali tasdiqlanganThe corresponding 2-propargyloxynaphthalene was synthesized by alkylating beta-naphthol with propargyl bromide. 2-bromo-4-nitrophenylazide was obtained by diazotization of 2-bromo-4-nitroaniline and then by treating it with sodium azide. The cycloaddition reaction of the synthesized propargyl ether and aromatic azide was studied. As a result of the cycloaddition, the 1,4-isomer derivative of 1H-1,2,3-triazole, 1-(2-bromo-4-nitrophenyl)-4-((naphthalen-2-yloxy)methyl)-1H-1,2,3-triazole, was formed. The effects of catalyst, temperature, and solvents on the reaction were studied. The structures of the synthesized substances were confirmed by IR and NMR spectra