ОЦЕНКА СПЕЦИФИЧЕСКИХ НАРУШЕНИЙ ПОЛЕЙ ЗРЕНИЯ ПРИ АГРЕССИВНЫХ АДЕНОМАХ ГИПОФИЗА

Relevance. Neuro-ophthalmological examination and assessment of specific visual field changes in patients play a key role in the non-invasive diagnosis of aggressive pituitary adenomas (APA), particularly in cases with aggressive progression. Purpose of the study. To evaluate the prevalence of visual field defects and their correlation with neuroimaging characteristics in aggressive pituitary adenomas (APA). Materials and methods.The study included 100 patients with a clinically confirmed diagnosis of APA. According to the study objectives, all patients were divided into two main groups: Group I – 35 patients with non-invasive adenomas, and Group II – 65 patients with invasive adenomas. Group II was further subdivided into two subgroups: IIA – 26 patients with invasive adenomas of growth grades 1-2, and IIB – 39 patients with grades 3-4 invasiveness. The neuro-ophthalmological assessment included the following examinations: evaluation of visual acuity, assessment of visual fields, and fundus examination. Results and conclusion. . In patients with suprasellar growth of invasive adenomas, the frequency of visual complaints in Groups IIA and IIB was 50% (n=13) and 43.6% (n=17), respectively. Visual field constriction was found in 26.9% (n=7) and 66.7% (n=26), respectively, which was significantly higher (p<0.001) compared to non-invasive adenomas. Neuroimaging evaluation revealed that in invasive adenomas of grades 3-4 (Group IIB), chiasmal compression was observed in 97.4% (n=38) of cases. The findings indicate that visual field defects are not only asignificant indicator of the invasiveness and aggressive nature of adenomas but also a marker of treatment effectiveness.

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