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Tailored pyrrole-based imidazothiazole scaffolds: Synthetic elaboration, enzyme kinetic profiling and DFT-guided molecular docking toward Antidiabetic therapeutics

Zanib FiazDepartment of Chemistry, Abbottabad University of Science and Technology, Abbottabad 22500, PakistanShoaib KhanDepartment of Chemistry, Abbottabad University of Science and Technology, Abbottabad 22500, Pakistan. Electronic address: [email protected]Tayyiaba IqbalDepartment of Chemistry, Abbottabad University of Science and Technology, Abbottabad 22500, PakistanWajid RehmanDepartment of Chemistry, Hazara University, Mansehra 21120, PakistanAnila FareedDepartment of Biochemistry,Abdul Wali Khan University, Mardan 23200, PakistanRafaqat HussainCollege of Biology, Hunan University, Changsha, Hunan 410082, PR ChinaKayumov Khasan Yusuf OgliNational University of Uzbekistan named after Mirza Ulugbek, Tashkent, UzbekistanMerajuddin KhanDepartment of Chemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi ArabiaMohammed Rafi ShaikDepartment of Chemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia. Electronic address: [email protected]

Computational Biology and Chemistryjournal2026en

ABI

Annotatsiya

Annotatsiya mavjud emas.

Mavzular

Natural Antidiabetic Agents Studies Synthesis and biological activity Enzyme function and inhibition

Identifikatorlar

DOI: 10.1016/j.compbiolchem.2026.108920

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