CONTEMPORARY APPROACHES TO HORMONAL THERAPY IN MALIGNANT PROSTATE TUMORS

Resume. This article analyzes the outcomes of hormonal treatment in 116 patients diagnosed with malignant tumors of the prostate gland. Current androgen deprivation strategies, including surgical castration, the use of luteinizing hormone–releasing hormone (LHRH) analogues and antagonists, as well as antiandrogen agents, are reviewed. Treatment efficacy was evaluated based on clinical and laboratory indicators, along with overall and recurrence-free survival rates. The findings demonstrate the high therapeutic effectiveness of combined hormonal therapy and highlight its potential for optimizing treatment strategies in patients with advanced prostate cancer. Keywords: prostate cancer; hormonal therapy; androgen deprivation; LHRH analogues; antiandrogens.

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