RESULTS OF MORPHOLOGICAL AND MORPHOMETRIC CHANGES IN THE RECTUM AS A RESULT OF CHEMOTHERAPY IN EXPERIMENTAL BREAST CANCER

Resume. In a study of the small intestinal mucosa of mice, the height of the intestinal villi increased by 35% when following a high-calorie diet containing 10% fat (417 µm in the control group and 563 µm in the experimental group). A decrease in the number of absorptive areas per mm² in the rectum was observed in rats maintained on a diet with 32% fat content. Experimental models showed an enlargement of the intestinal cavity, which leads to the development of obesity. Standard nutrition over a period of 5 weeks (a diet with 14% fat content) showed signs of inflammation developing in the epithelium of the rectal mucosa. Keywords: breast cancer, rectum, morphology, chemotherapy.

Hali tarjima qilinmagan