Modern Perspectives on The Impact of Comorbidities on The Course of Covid-19 In Children
Annotatsiya
This article analyzes contemporary scientific literature regarding the impact of comorbidities on the course of COVID-19 in children. Obesity, diabetes mellitus, cardiovascular diseases, chronic lung diseases, neurological disorders, and immunodeficiency states are examined as independent risk factors for a severe course of COVID-19. Pathogenetic mechanisms, including cytokine storm, increased inflammatory markers, and T-cell immunity dysfunction, are described in detail. The article also highlights the clinical significance of MIS-C syndrome, its diagnostic criteria, modern treatment approaches, and vaccination recommendations.