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Characteristics of Tlr6 Receptor Expression in Patients with Bronchial Asthma

Shamsiev F.M.Republican Specialized Scientific and Practical Medical Center of Pediatrics, Tashkent, UzbekistanAzizova N.D.Republican Specialized Scientific and Practical Medical Center of Pediatrics, Tashkent, UzbekistanMusajanova R.A.Republican Specialized Scientific and Practical Medical Center of Pediatrics, Tashkent, UzbekistanAbdullaeva M.K.Republican Specialized Scientific and Practical Medical Center of Pediatrics, Tashkent, UzbekistanKarimova M. Kh.Republican Specialized Scientific and Practical Medical Center of Pediatrics, Tashkent, UzbekistanUzakova Sh.B.Republican Specialized Scientific and Practical Medical Center of Pediatrics, Tashkent, Uzbekistan
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The aim of this study was to investigate the features of innate immunity receptor (TLR6) expression in patients with bronchial asthma (BA). The study examined 45 pediatric patients with BA aged 5 to 15 years. The comparison group consisted of 31 children with recurrent obstructive bronchitis (ROB). Genetic research methods were used during the comprehensive clinical and laboratory examination of the children. The results demonstrated a significant role of the TLR6 gene in forming predisposition to BA. The obtained data will contribute to a better understanding of the subsequent development of BA involving TLR6.

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