ACUTE BILIARY PANCREATITIS: AGE AND GENDER DIFFERENCES IN CLINICAL PRESENTATION

Resume. Objective. To assess the frequency of biliary etiology among patients with acute pancreatitis and to analyze the age- and sex-related characteristics of acute biliary pancreatitis. Materials and Methods. A retrospective analysis was performed of the medical records of 302 patients admitted to the surgical departments of the Republican Scientific Center of Emergency Medical Care in 2022-2025 with a preliminary diagnosis of acute pancreatitis. Patients transferred from other hospitals, including those after recently performed endoscopic papillosphincterotomy, were excluded from the study. The diagnosis was established according to the Revised Atlanta Classification and the 2012 international consensus. Results. The diagnosis of acute pancreatitis was confirmed in 255 of 302 patients (84.4%). Biliary etiology was identified in 225 of 255 confirmed cases (88.2%). Among patients with acute biliary pancreatitis, women accounted for 71.1% and men for 28.9%. No statistically significant difference in mean age was found between women and men (52.0±18.2 vs. 52.9±16.4 years; p=0.642). The female-to-male ratio varied across age groups, reaching its highest value in middle age and decreasing in older patients. Conclusion. Acute biliary pancreatitis was the predominant form of acute pancreatitis in the studied cohort. The limited sensitivity of transabdominal ultrasonography and the low sensitivity of ALT elevation support the need for a comprehensive diagnostic approach using additional imaging modalities. Keywords: acute biliary pancreatitis, gallstone disease, cholelithiasis, age, sex, diagnosis, ultrasonography, alanine aminotransferase.

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