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Ish: Recent developments regarding the use of thieno[2,3-d]pyrimidin-4-one derivatives in medicinal chemistry, with a focus on their synthesis and anticancer properties

Thieno[2,3-d]pyrimidin-4-ones 1. Condensation of 2,3-dimethyl- and 2,3-tri-, 2,3-tetra-, and 2,3-pentamethylene-7,8-dihydro-pyrrolo[1,2-a]thieno[2,3-d]pyriminidin-4(6H)-ones with aromatic aldehydes and furfural
Burkhon Elmuradov, Khurshed Bozorov, Kh. М. Shakhidoyatov
MaqolaSynthesis of heterocyclic compoundsChemistry of Heterocyclic Compounds201119 iqtibos
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Synthesis and Biological Evaluation of 17β-Hydroxysteroid Dehydrogenase Type 1 (17β-HSD1) Inhibitors Based on a Thieno[2,3-d]pyrimidin-4(3H)-one Core
Annamaria Lilienkampf, Sampo Karkola, Sari Alho-Richmond +5
Maqola20095 iqtibos
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Synthesis and biological evaluation of thieno[2,3-d]pyrimidine derivatives for anti-inflammatory, analgesic and ulcerogenic activity
Abdel-Rahman B.A. El-Gazzar, Hoda A. R. Hussein, Hend N. Hafez
Maqola20074 iqtibos
ABI
Synthesis, Characterization and Biological Studies of Some Novel Thieno[2,3-d]pyrimidines
Khulud M. Al-Taisan, H.M.A. Al-Hazimi, Shar S. Al‐Shihry
Maqola20104 iqtibos
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Thieno[2,3-d ]Pyrimidin-4-Ones. Part 2*. Condensation of 2,3- Disubstituted Thieno[2,3-d]Pyrimidin-4-Ones with Aldehydes
Burkhon Elmuradov
MaqolaSynthesis and Reactions of Organic CompoundsAmerican Chemical Science Journal20134 iqtibos
ABI
Thieno[2,3-d]Pyrimidin-4-Ones. Part 3.* Electrophilic Ipso-Substitution Reactions of Methyl and Methoxycarbonyl Groups
Burkhon Elmuradov
MaqolaSynthesis and Reactions of Organic CompoundsAmerican Chemical Science Journal20134 iqtibos
ABI
Heterocyclic Scaffolds: Centrality in Anticancer Drug Development
Imran Ali, Mohammad Lone, Zeid A. ALOthman +2
Sharh maqola20153 iqtibos
ABI
Synthesis, antitumor and antibacterial activities of some novel tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine derivatives
Safinaz E. Abbas, Nagwa M. Abdel Gawad, Riham F. George +1
Maqola20133 iqtibos
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Recent Report on Thieno[2,3-d]pyrimidines. Their Preparation Including Microwave and Their Utilities in Fused Heterocycles Synthesis
Ashraf A. Aly, Esam A. Ishak, Mohamed Ramadan +3
Maqola20133 iqtibos
ABI
Thienopyrimidines: synthesis, properties, and biological activity
В. П. Литвинов
Maqola20043 iqtibos
ABI
Synthesis and anticancer activity of novel 2-pyridyl hexahyrocyclooctathieno[2,3-d]pyrimidine derivatives
Asmaa E. Kassab, Ehab M. Gedawy
Maqola20132 iqtibos
ABI
A convenient method for constructing novel tetrahydropyrido[4′,3′:4,5]thieno[2,3-d]-pyrimidinones-carbohydrate and amino acid conjugates via copper(I)-catalyzed alkyne-azide ‘Click Chemistry’
Mohamed A. Ameen, Sebastian Karsten, Jürgen Liebscher
Maqola20102 iqtibos
ABI
Synthesis and antiproliferative activity of some new thieno[2,3-d]pyrimidin-4(3H)-ones containing 1,2,4-triazole and 1,3,4-thiadiazole moiety
Anelia Ts. Mavrova, Diana Wesselinova, Jordan A. Tsenov +1
Maqola20142 iqtibos
ABI
C–C (alkynylation) vs C–O (ether) bond formation under Pd/C–Cu catalysis: synthesis and pharmacological evaluation of 4-alkynylthieno[2,3-d]pyrimidines
Dhilli Rao Gorja, K. Shiva Kumar, K. Mukkanti +1
Maqola20112 iqtibos
ABI
Diversification of a Thieno[2,3-d]pyrimidin-4-one Scaffold via Regioselective Alkylation Reactions
Sergey G. Dzhavakhishvili, Nikolay Yu. Gorobets, Svitlana Shishkina +3
Maqola20092 iqtibos
ABI
Combining Hit Identification Strategies: Fragment-Based and in Silico Approaches to Orally Active 2-Aminothieno[2,3-d]pyrimidine Inhibitors of the Hsp90 Molecular Chaperone
Paul A. Brough, Xavier Barril, Jenifer Borgognoni +30
Maqola20092 iqtibos
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Ushbu ish iqtibos qilgan ishlar

Thieno[2,3-d]pyrimidin-4-ones 1. Condensation of 2,3-dimethyl- and 2,3-tri-, 2,3-tetra-, and 2,3-pentamethylene-7,8-dihydro-pyrrolo[1,2-a]thieno[2,3-d]pyriminidin-4(6H)-ones with aromatic aldehydes and furfural

Synthesis and Biological Evaluation of 17β-Hydroxysteroid Dehydrogenase Type 1 (17β-HSD1) Inhibitors Based on a Thieno[2,3-<i>d</i>]pyrimidin-4(3<i>H</i>)-one Core

Synthesis and biological evaluation of thieno[2,3-d]pyrimidine derivatives for anti-inflammatory, analgesic and ulcerogenic activity

Synthesis, Characterization and Biological Studies of Some Novel Thieno[2,3-d]pyrimidines

Thieno[2,3-d ]Pyrimidin-4-Ones. Part 2*. Condensation of 2,3- Disubstituted Thieno[2,3-d]Pyrimidin-4-Ones with Aldehydes

Thieno[2,3-d]Pyrimidin-4-Ones. Part 3.* Electrophilic Ipso-Substitution Reactions of Methyl and Methoxycarbonyl Groups

Heterocyclic Scaffolds: Centrality in Anticancer Drug Development

Synthesis, antitumor and antibacterial activities of some novel tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine derivatives

Recent Report on Thieno[2,3-<i>d</i>]pyrimidines. Their Preparation Including Microwave and Their Utilities in Fused Heterocycles Synthesis

Thienopyrimidines: synthesis, properties, and biological activity

Synthesis and anticancer activity of novel 2-pyridyl hexahyrocyclooctathieno[2,3-d]pyrimidine derivatives

A convenient method for constructing novel tetrahydropyrido[4′,3′:4,5]thieno[2,3-d]-pyrimidinones-carbohydrate and amino acid conjugates via copper(I)-catalyzed alkyne-azide ‘Click Chemistry’

Synthesis and antiproliferative activity of some new thieno[2,3-d]pyrimidin-4(3H)-ones containing 1,2,4-triazole and 1,3,4-thiadiazole moiety

C–C (alkynylation) vs C–O (ether) bond formation under Pd/C–Cu catalysis: synthesis and pharmacological evaluation of 4-alkynylthieno[2,3-<i>d</i>]pyrimidines

Diversification of a Thieno[2,3-<i>d</i>]pyrimidin-4-one Scaffold via Regioselective Alkylation Reactions

Combining Hit Identification Strategies: Fragment-Based and in Silico Approaches to Orally Active 2-Aminothieno[2,3-<i>d</i>]pyrimidine Inhibitors of the Hsp90 Molecular Chaperone

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