The Future of Genetic Studies of Complex Human Diseases
Neil RischN. Risch is in the Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305-5120, USAKathleen R. MerikangasK. Merikangas is in the Departments of Epidemiology and Psychiatry Unit, Yale University School of Medicine, New Haven, CT 06510, USA
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The identification of the genetic basis of complex human diseases such as schizophrenia and diabetes has proven difficult. In their Perspective, Risch and Merikangas propose that we can best accomplish this goal by combining the power of the human genome project with association studies, a method for determining the basis of a genetic disease.
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