Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
Andrew P. MorrisWellcome Trust Centre for Human Genetics, University of Oxford, UK. [email protected]Benjamin F. VoightBroad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USATanya M. TeslovichDepartment of Biostatistics, University of Michigan, Ann Arbor, Michigan, USATeresa FerreiraWellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UKAyellet V. SegrèBroad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USAValgerður SteinthórsdóttirdeCODE Genetics, Reykjavik, IcelandRona J. StrawbridgeCenter for Molecular Medicine, Karolinska University Hospital Solna, Stockholm, SwedenHassan KhanDepartment of Public Health and Primary Care, University of Cambridge, Cambridge, UKHarald GrallertResearch Unit of Molecular Epidemiology, Helmholtz Zentrum Muenchen, Neuherberg, GermanyAnubha MahajanWellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UKInga ProkopenkoOxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UKHyun Min KangDepartment of Biostatistics, University of Michigan, Ann Arbor, Michigan, USAChristian DinaCentre National de la Recherche Scientifique (CNRS) UMR 6291, Nantes, FranceTõnu EskoEstonian Genome Center, University of Tartu, Tartu, EstoniaRoss M. FraserCentre for Population Health Sciences, University of Edinburgh, Edinburgh, UKStavroula KanoniWellcome Trust Sanger Institute, Hinxton, Cambridge, UKAshish KumarWellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UKVasiliki LagouWellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UKClaudia LangenbergMedical Research Council (MRC) Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UKJian’an LuanMedical Research Council (MRC) Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UKCecilia M. LindgrenWellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UKMartina Müller‐NurasyidDepartment of Medicine I, University Hospital Grosshadern, Ludwig-Maximilians-Universität, Munich, GermanySonali PechlivanisInstitute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, University Duisburg-Essen, Essen, GermanyNigel W. RaynerOxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UKLaura J. ScottDepartment of Biostatistics, University of Michigan, Ann Arbor, Michigan, USASteven WiltshireWellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UKLoïc YengoCNRS UMR 8199, Institute of Biology and Lille 2 University, Pasteur Institute, Lille, FranceLeena KinnunenDiabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, FinlandElizabeth J. RossinBroad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USASoumya RaychaudhuriBroad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USAAndrew D. JohnsonNational Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, Massachusetts, USAAntigone S. DimasBiomedical Sciences Research Center Al Fleming, Vari, GreeceRuth J. F. LoosCharles R Bronfman Institute for Personalized Medicine, Mount Sinai School of Medicine, New York, New York, USASailaja VedantamDivision of Genetics and Endocrinology, Children's Hospital, Boston, Massachusetts, USAHan ChenDepartment of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USAJosé C. FlorezCenter for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USACaroline S. FoxDivision of Endocrinology and Metabolism, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USAChing‐Ti LiuDepartment of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USADenis RybinBoston University Data Coordinating Center, Boston, Massachusetts, USADavid CouperDepartment of Biostatistics, Collaborative Studies Coordinating Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USAWen Hong Linda KaoDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USAMan LiDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USAMarilyn C. CornelisDepartment of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USAPeter KraftDepartment of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USAQi SunDepartment of Medicine, Channing Laboratory, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USARob M. van DamDepartment of Nutrition and Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USAHeather M. StringhamDepartment of Biostatistics, University of Michigan, Ann Arbor, Michigan, USAPeter S. ChinesNational Human Genome Research Institute, US National Institutes of Health, Bethesda, Maryland, USAKrista FischerEstonian Genome Center, University of Tartu, Tartu, EstoniaPierre FontanillasBroad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USAOddgeir L. HolmenDepartment of Public Health and General Practice, Nord-Trondelag Health Study (HUNT) Research Centre, Norwegian University of Science and Technology, Levanger, NorwaySarah HuntWellcome Trust Sanger Institute, Hinxton, Cambridge, UKAnne JacksonDepartment of Biostatistics, University of Michigan, Ann Arbor, Michigan, USAAugustine KongdeCODE Genetics, Reykjavik, IcelandRobert LawrenceCentre for Genetic Epidemiology and Biostatistics, The University of Western Australia, Nedlands, Western Australia, AustraliaJulia MeyerInstitute of Genetic Epidemiology, Helmholtz Zentrum Muenchen, Neuherberg, GermanyJohn R. B. PerryGenetics of Complex Traits, Institute of Biomedical and Clinical Science, Peninsula Medical School, University of Exeter, Exeter, UKCarl PlatouDepartment of Internal Medicine, Levanger Hospital, Nord-Trøndelag Health Trust, Levanger, NorwaySimon PotterWellcome Trust Sanger Institute, Hinxton, Cambridge, UKEmil RehnbergDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, SwedenNeil RobertsonOxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UKSuthesh SivapalaratnamDepartment of Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The NetherlandsAlena StančákováDepartment of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, FinlandKathleen StirrupsWellcome Trust Sanger Institute, Hinxton, Cambridge, UKGuðmar ÞorleifssondeCODE Genetics, Reykjavik, IcelandEmmi TikkanenDepartment of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, FinlandAndrew R. WoodGenetics of Complex Traits, Institute of Biomedical and Clinical Science, Peninsula Medical School, University of Exeter, Exeter, UKPeter AlmgrenDepartment of Clinical Science Malmö, Lund University Diabetes Centre, Scania University Hospital, Lund University, Malmö, SwedenMustafa AtalayInstitute of Biomedicine, Physiology, University of Eastern Finland, Kuopio, FinlandRafn BenediktssonDepartment of Endocrinology and Metabolism, Landspitali University Hospital, Reykjavík, IcelandLori L. BonnycastleNational Human Genome Research Institute, US National Institutes of Health, Bethesda, Maryland, USANoël P. BurttBroad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USAJason CareyBroad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USAG. CharpentierEndocrinology-Diabetology Unit, Corbeil-Essonnes Hospital, Corbeil-Essonnes, FranceAndrew CrenshawBroad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USAAlex S. F. DoneyDiabetes Research Centre, Biomedical Research Institute, University of Dundee, Ninewells Hospital, Dundee, UKMozhgan DorkhanDepartment of Clinical Science Malmö, Lund University Diabetes Centre, Scania University Hospital, Lund University, Malmö, SwedenSarah EdkinsWellcome Trust Sanger Institute, Hinxton, Cambridge, UKValur EmilssonIcelandic Heart Association, Kopavogur, IcelandElodie EuryCNRS UMR 8199, Institute of Biology and Lille 2 University, Pasteur Institute, Lille, FranceTom ForsénDepartment of General Practice and Primary Health Care, University of Helsinki, Helsinki, FinlandKarl GertowCenter for Molecular Medicine, Karolinska University Hospital Solna, Stockholm, SwedenBruna GiganteDivision of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, SwedenGeorge GrantBroad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USAChristopher J. GrovesOxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UKCandace GuiducciBroad Institute of Harvard and Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USAChristian HerderInstitute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, GermanyÁstráður B. HreiðarssonDepartment of Endocrinology and Metabolism, Landspitali University Hospital, Reykjavík, IcelandJennie HuiBusselton Population Medical Research Institute, Sir Charles Gairdner Hospital, Nedlands, Western Australia, AustraliaAlan JamesBusselton Population Medical Research Institute, Sir Charles Gairdner Hospital, Nedlands, Western Australia, AustraliaAnna JonssonDepartment of Clinical Science Malmö, Lund University Diabetes Centre, Scania University Hospital, Lund University, Malmö, SwedenWolfgang RathmannInstitute of Biometrics and Epidemiology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Düsseldorf, Düsseldorf, GermanyNorman KloppResearch Unit of Molecular Epidemiology, Helmholtz Zentrum Muenchen, Neuherberg, GermanyJasmina KravićDepartment of Clinical Science Malmö, Lund University Diabetes Centre, Scania University Hospital, Lund University, Malmö, SwedenKaarel KrjutškovEstonian Genome Center, University of Tartu, Tartu, EstoniaCordelia LangfordWellcome Trust Sanger Institute, Hinxton, Cambridge, UKKarin LeanderDivision of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, SwedenEero LindholmDepartment of Clinical Science Malmö, Lund University Diabetes Centre, Scania University Hospital, Lund University, Malmö, SwedenStéphane LobbensCNRS UMR 8199, Institute of Biology and Lille 2 University, Pasteur Institute, Lille, FranceSatu MännistöDepartment of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland
2012en
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