Studies on the nepalese crude drugs. XIII. On the flavonoid and iridoid constiuents of the root of Scutellaria grossa Wall.

From the root of Scutellaria grossa WALL, three new natural flavonoids (I-III) were isolated, together with fifteen known flavonoids (IV, VIII-XXI), two iridoids (V and VI) and trans-cinnamic acid (VII). The structures of I-III were shown to be 5-hydroxy-7, 8, 2', 6'-tetramethoxyflavone, 5, 6, 2'-trihydroxy-7, 8-dimethoxyflavone and (2S)-5-hydroxy-7, 8, 2', 6'-tetramethoxyflavonone, respectively, on the basis of the chemical and spectral data. Compound I has a already been synthesized.

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