Studies on the nepalese crude drugs. IX. On the flavonoid constituents of the root of scutellaria scandens BUCH.-HAM. ex D. DON.

From the root of Scutellaria scandens BUCH.-HAM. ex D. DON, five new flavanones (I-V) were isolated, together with oroxylin A, dihydrooroxylin A, wogonin, chrysin, baicalein, dihydrobaicalein, norwogonin, wogonin 7-O-glucuronide, chrysin 7-O-glucuronide, baicalin and dihydrobaicalin. Compounds I-V were identified as (2S)-5, 7, 2', 5'-tetrahydroxy-6-methoxyflavanone, (2S)-5, 7, 2', 5'-tetrahydroxy-6-methoxyflavanone 2'-O-β-D-glucopyranoside, (2S)-5, 7, 2', 5'-tetrahydroxy-6-methoxyflavanone 2'-O-β-D-(2-O-feruloyl)glucopyranoside, (2S)-5, 7, 2', 5'-tetrahydroxy-6-methoxyflavanone 2'-O-β-D-(2-O-sinapoyl)glucopyranoside and (2S)-5, 7, 2', 5'-tetrahydroxy-6-methoxyflavanone 2'-O-β-D-(2-O-vanilloyl)glucopyranoside, respectively, based on spectral and chemical data.

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