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PhyloBayes 3: a Bayesian software package for phylogenetic reconstruction and molecular dating

Nicolas Lartillot1 Département de Biochimie, Université de Montréal, Montréal, Québec, Canada and 2 Département d'Informatique, LIRMM, Montpellier, FranceThomas Lepage1 Département de Biochimie, Université de Montréal, Montréal, Québec, Canada and 2 Département d'Informatique, LIRMM, Montpellier, FranceSamuel BlanquartUniversité de Montréal
2009en
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Abstract Motivation: A variety of probabilistic models describing the evolution of DNA or protein sequences have been proposed for phylogenetic reconstruction or for molecular dating. However, there still lacks a common implementation allowing one to freely combine these independent features, so as to test their ability to jointly improve phylogenetic and dating accuracy. Results: We propose a software package, PhyloBayes 3, which can be used for conducting Bayesian phylogenetic reconstruction and molecular dating analyses, using a large variety of amino acid replacement and nucleotide substitution models, including empirical mixtures or non-parametric models, as well as alternative clock relaxation processes. Availability: PhyloBayes is freely available from our web site http://www.phylobayes.org. It works under Linux, Mac OsX and Windows operating systems. Contact: [email protected] Supplementary information: Supplementary data are available at Bioinformatics online.

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