Transdermal delivery of multifunctional CaO<sub>2</sub>@Mn-PDA nanoformulations by microneedles for NIR-induced synergistic therapy against skin melanoma
Liming RuanSong GaoSchool of Materials Science and Engineering, Zhejiang Sci-Tech University, Hangzhou, Zhejiang 310018, ChinaXueya ZhangSchool of Materials Science and Engineering, Zhejiang Sci-Tech University, Hangzhou, Zhejiang 310018, ChinaTianqi LiuSchool of Materials Science and Engineering, Zhejiang Sci-Tech University, Hangzhou, Zhejiang 310018, ChinaYanfang SunCollege of Life Sciences and Medicine, Zhejiang Sci-Tech University, Hangzhou, Zhejiang 310018, ChinaJunlan ZhuZhiyong ZengSchool of Materials Science and Engineering, Zhejiang Sci-Tech University, Hangzhou, Zhejiang 310018, ChinaGuohua JiangSchool of Materials Science and Engineering, Zhejiang Sci-Tech University, Hangzhou, Zhejiang 310018, China
2021en
ABI
Annotatsiya
The CaO 2 @Mn-PDA nanoformulations, integrated with photothermal conversion of Mn-PDA, CDT of doped Mn ions, and relieve hypoxia in TME of CaO 2 , were developed for NIR-induced synergistic therapy against melanoma by microneedles transdermal delivery.
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