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The Nairobi Declaration—Reducing the burden of dementia in low‐ and middle‐income countries (LMICs): Declaration of the 2022 Symposium on Dementia and Brain Aging in LMICs

Gladys E. MaestreDepartments of Neuroscience and Human Genetics University of Texas Rio Grande Valley Brownsville TX USAMaria CarrilloAlzheimer's Association Chicago IL USARaj N. KalariaTranslational and Clinical Research Institute Newcastle University, Campus for Ageing and Vitality Newcastle upon Tyne UKDaisy AcostaInternal Medicine Department Universidad Nacional Pedro Henriquez Ureña Santo Domingo Dominican RepublicLarry AdamsInstitute of Human Genomics University of Miami Miami FL USAThierry AdoukonouDepartment of Neurology University of Parakou Parakou BeninKazeem AkinwandeDepartment of Chemical Pathology and Immunology, Federal Medical Centre Abeokuta NigeriaJoshua AkinyemiCollege of Medicine University of Ibadan Ibadan NigeriaRufus AkinyemiInstitute for Advanced Medical Research and Training University of Ibadan Ibadan NigeriaOnoja AkpaCollege of Medicine University of Ibadan Ibadan NigeriaSuvarna AlladiDepartment of Neurology NIMHANS Bangalore IndiaRicardo AllegriDepartment of Cognitive Neurology, Instituto Neurologico Fleni Buenos Aires ArgentinaRaúl L. ArizagaNeurología Cognitiva y Neuropsicología, Hospital Dr. Cesar Milstein Buenos Aires ArgentinaFaheem ArshadDepartment of Neurology, NIMHANS Bengaluru IndiaOyedunni ArulogunDepartment of Health Promotion and Education University of Ibadan Ibadan NigeriaDavid Oluwasayo BabalolaUniversity College Hospital University of Ibadan Ibadan NigeriaOlusegun BaiyewuDepartment of Psychiatry University of Ibadan Ibadan NigeriaThomas H. BakDepartment of Neurology University of Edinburgh Edinburgh UKTarek BellajDepartment of Psychological Sciences Qatar University Doha QatarJudith BosheDepartment of Medicine Kilimanjaro Christian Medical College Moshi TanzaniaCarol BrayneCambridge Public Health University of Cambridge Cambridge UKDavid K. Brodie‐MendsDepartment of Medicine Korle‐Bu Teaching Hospital Accra GhanaRichard BrownDepartment of Psychology, Dalhousie University Halifax CanadaJennifer CahnDepartments of Neuroscience and Human Genetics University of Texas Rio Grande Valley Brownsville TX USACyrille NkouonlackFaculty of Health Sciences, University of Buea, Buea & Brain Research Africa Initiative Yaounde CameroonAlbertino DamascenoDepartment of Medicine University of Maputo Maputo MozambiqueRanil de SilvaFaculty of Medical Sciences University of Sri Jayewardenepura Rathmalana Sri LankaRohan de SilvaFaculty of Medical Sciences University of Sri Jayewardenepura Rathmalana Sri LankaMamuka DjibutiPartnership for Research and Action for Health Tbilisi GeorgiaAnna J. DreyerDepartment of Psychiatry and Mental Health University of Cape Town Cape Town South AfricaRatnavalli EllajosyulaDepartment of Neurology Manipal Hospitals Bangalore IndiaTemitope FarombiDepartment of Neurology University of Ibadan Ibadan NigeriaBernard FongangGlenn Biggs Institute University of Texas San Antonio TX USAStefânia FornerAlzheimer's Association Chicago IL USARobert P. FriedlandDepartment of Neurology University of Louisville Louisville USANoe GarzaDepartments of Neuroscience and Human Genetics University of Texas Rio Grande Valley Harlingen TX USAAntoine Gbessemehlaninstitute of Epidemiology and Tropical Neurology University of Limoges Bordeaux FranceEliza GeorgiouDepartment of Psychiatry, Medicine University of Patras Patras GreeceRiadh GouiderNeurology Department Razi University Hospital Tunis TunisiaIshtar GoviaCaribbean Institute for Health Research University of the West Indies Kingston JamaicaLea T. GrinbergDepartment of Neurology University of San Francisco San Francisco CA USAMaëlenn GuerchetInserm U1094, IRD UMR270, Univ. Limoges, CHU Limoges, EpiMaCT ‐ Epidemiology of chronic diseases in tropical zone, Institute of Epidemiology and Tropical Neurology, OmegaHealth Limoges FranceSeid Ali GugssaDepartment of Neurology, Addis Ababa University Addis Ababa EthiopiaJoy Louise Gumikiriza‐OnoriaDepartment of Psychiatry, Makerere University Kampala UgandaDeborah GustafsonDepartment of Neurology, State University of New York Downstate Health Sciences University Brooklyn NY USAEef HogervorstDepartment of Psychology University of Loughborough Loughborough UKMichael HornbergerDepartment of Neurology University of East Anglia Norwich UKAgustín IbáñezGlobal Brain Health Institute, Trinity College Dublin IrelandMasafumi IharaDepartment of Neurology, National Cerebral and Cardiovascular Center Suita JapanOzama IsmailAlzheimer's Association Chicago IL USAThomas Gregor IssacCentre for Brain Research (CBR), Indian Institute of Science (IISc) Bengaluru IndiaLinus JönssonDepartment of Neurobiology, Care Sciences and Society, Karolinska Institutet SwedenCelestin KaputuDepartment of Neurology University of Kinshasa Kinshasa Democratic Republic of the CongoWambūi KaranjaGlobal Brain Health Institute Trinity College Nairobi KenyaJackline KarungiDepartment of Psychiatry Makerere University Kampala UgandaDésiré Tshala-KatumbayDepartment of Neurology Oregon Health & Science University Portland OR USABrian W. KunkleInstitute of Human Genomics University of Miami Miami FL USAJoseph H. LeeSergievsky Center & Taub Institute Columbia University New York NY USAIracema LeroiTCIN, Lloyd Building Trinity College Dublin IrelandRaphaella LewisDepartment of Psychology University of Cape Town Cape Town South AfricaGill LivingstonDepartment of Psychiatry University College London London UKFrancisco LoperaGrupo de Neurociencias de Antioquia Universidad de Antioquia Medellin ColombiaKamada LwereDepartment of Medical Microbiology Makerere University Mulago UgandaFacundo ManesInstitute of Cognitive and Translational Neuroscience (INCYT), INECO Foundation Favaloro University Buenos Aires ArgentinaLingani Mbakile‐MahlanzaDepartment of Psychology University of Botswana Gabrone BotswanaPedro MenaInstitute of Human Genomics University of Miami Miami FL USABruce L. MillerDepartment of Neurology University of San Francisco San Francisco CA USAAthanase MillogoDepartment of Neurology University of Ouagadougou Ouagadougou Burkina FasoAbdul MohamedDepartment of Psychology Linnaeus University Vaxjo SwedenChristine MusyimiAfrican Mental Health Research & Training Foundation Nairobi KenyaVictoria MutisoAfrican Mental Health Research & Training Foundation Nairobi KenyaNoeline NakasujjaDepartment of Psychiatry Makerere University Kampala UgandaDavid M. NdeteiAfrica Mental Health Research and Training Foundation and University of Nairobi Nairobi KenyaSam NightingaleDepartment of Neurology University of Cape Town Cape Town South AfricaAlfred K. NjamnshiDepartment of Neurology, FMBS, The University of Yaoundé I & Brain Research Africa Initiative Yaounde CameroonGabriela NovotniDepartment of Neurology Ss. Cyril and Methodius University Skopje North MacedoniaPrimrose NyamayaroDepartment of Psychology University of Harare Harare ZimbabweSolomon NyameKintampo Health Research Centre, Ghana Health Service Kintampo GhanaJulius A Ogeng’oDepartment of Human Anatomy & Medical Physiology University of Nairobi Nairobi KenyaAdesola OgunniyiDepartment of Medicine University of Ibadan Ibadan NigeriaMaira Okada de OliveiraCognitive and Behavioral Neurology Unit University of São Paulo São Paulo SP BrazilNjideka OkubadejoNeurology Unit, Department of Medicine, College of Medicine, University of Lagos NigeriaMartin OrrellInstitute of Mental Health University of Nottingham Nottingham UKAkintunde T. OrunmuyiIntegrated Molecular Imaging Centre Kenyatta University Nairobi KenyaMayowa OwolabiCenter for Genomic and Precision Medicine, College of Medicine University of Ibadan Ibadan NigeriaStella‐Maria PaddickTranslational and Clinical Research Institute Newcastle University Newcastle upon Tyne UKMargaret A Pericak‐VanceInstitute of Human Genomics University of Miami Miami FL USAZvezdan PirtošekDepartment of Neurology, Ljubljana University Medical Centre Ljubljana SloveniaFelix PotocnikDepartment of Geriatric Psychiatry, Stellenbosch University Durbanville South AfricaBill PrestonRoots Worldwide LLC and Innovative California Biosciences International Inc Fullerton CA USARema RamanAlzheimer's Therapeutic Research Institute, University of Southern California San Diego CA USAKirti RanchodGlobal Brain Health Institute, Trinity College Johannesburg South AfricaMie RizigUCL Queen Square Institute of Neurology London UKMónica RosselliDepartment of Psychology Florida Atlantic University Miami FL USADeepa RoyDepartment of Health and Biomedical Science The University of Texas Rio Grande Valley Brownsville TX USAUpal Kunal Basu RoyDepartment of Health and Biomedical Science The University of Texas Rio Grande Valley Brownsville TX USAM. SalokhiddinovZangiota‐2 Clinical Hospital Tashkent Medical Academy Tashkent UzbekistanMary SanoAlzheimer's Disease Center Mount Sinai School of Medicine Bronx NY USAFred Stephen SarfoDepartment of Medicine Kwame Nkrumah University of Science & Technology Kumasi GhanaClaudia L. SatizábalGlenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases and Department of Population Health Sciences, UT Health San Antonio San Antonio Texas United States
Alzheimer s & Dementiajournal2023en
ABI

Annotatsiya

Delegates of the 2022 Symposium on Dementia and Brain Aging in Low- and Middle-Income Countries, representing over 40 countries, met in Nairobi, Kenya, December 5–9 to highlight advances in dementia prevention, diagnosis, care, and research, as well as explore the future needs of the global community. Dementia poses a major threat to optimal brain health and remains a priority for the demographically ever-changing worldwide population. It incurs substantial individual, societal, and global costs. By 2030, the majority of the 78 million people with dementia will be living in low- and middle-income countries (LMICs). Upon consideration of these grave statistics and new diagnostic paradigms with available prevention and treatment strategies, we, the undersigned delegates of the symposium, including the Organizing Committee and speakers, and the African Dementia Consortium (AfDC), with frontline and lived experience, call upon the global community, including governments, policymakers, international economic forums, health and social care providers, together with private and public research funding agencies, research-focused organizations such as universities, nongovernmental organizations, and technology and pharmaceutical companies, to act as follows: Rethink a global approach to dementia, being more focused on the diversity of underserved and underrepresented populations. Shift the balance of investment further toward LMICs, which bear a high burden, to tackle the challenges and seize opportunities and to mitigate the burden of various forms of dementia, including Alzheimer's disease, vascular dementia, and others, globally. Engage and influence policymakers and advocacy organizations to encourage implementation and evaluation of population-level dementia risk reduction interventions at a more diverse global level. In addition to promoting education, controlling cardiovascular risk, and preventing stroke, seriously consider nutritional factors as well as psychosocial activities for brain health and longevity. Ensure that the health and social care systems are equipped to meet the needs of aging populations in the LMICs as well as low-resource settings in high-income countries (HICs). Support research into more affordable, pragmatic, and effective solutions to improve the quality of life of people living with dementia and reduce the expenses of hospitalization, long-term care, and loss of income and indirect costs resulting from dementia. Equip higher education institutions in HICs and LMICs with the capacity to develop a pipeline of local highly motivated early career researchers (ECRs) to ensure future research will be responsive to local population needs and to leverage opportunities offered by different countries. Ensure a research framework with international collaboration that will unwind the rigid structures in LMICs and encourage young, enthusiastic people to give the best of their potential in their countries, thereby preventing brain drain. We believe that timely intervention to address these goals will bring about significant and sustainable improvements in the prevalence, outcomes, and personal and societal impacts of dementia, resulting in a higher quality of life, better care, and global benefits. Nairobi, Kenya, December 9, 2022 Organizing Committee and Speakers of the 2022 Symposium on Dementia and Brain Aging in Low- and Middle-Income Countries.

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