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Synthesis and biological activities of local anesthetics

Shiyang ZhouChinaGangliang HuangActive Carbohydrate Research InstituteGuang‐Ying ChenChina
2019en
ABI

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passage through sodium ion channels, thus blocking the generation and conduction of nerve impulses, reversibly blocking the generation and conduction of sensory nerve impulses. Local anesthetics are used for convenience in local surgical operations and treatments. Herein, we mainly review the research progress on local anesthetics and discuss the important aspects of design, synthesis and biological activity of various new compounds.

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