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Mild and efficient one-pot synthesis of (E)-styrylperfluoroalkyl ketone from styrene

V. Raghavender RaoDepartment of Chemistry, Changwon National University, Changwon, GN 51140, South KoreaKalpesh PatilDepartment of Chemistry, Changwon National University, Changwon, GN 51140, South KoreaDeepak KumarDepartment of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Shoolini University, Solan 173 229, H.P., IndiaManoj K. GuptaDepartment of Chemistry, School of Basic Sciences, Central University of Haryana, Mahendergarh 123031, Haryana, IndiaDong‐Soo ShinDepartment of Chemistry, Changwon National University, Changwon, GN 51140, South Korea
2021en
ABI

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An easy and highly efficient one-pot synthesis of (E)-styrylperfluoroalkyl ketone from styrene using trifluoro-, pentafluoro-, heptafluoroacetic anhydride has been developed. This procedure mainly works on substituted styrene having electron donating groups which provide driving force to accelerate the reaction under base-free condition.

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