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α‐Ecdysone, a new bracken fern factor responsible for neoplasm induction in the Egyptian toad (<i>Bufo regularis</i>)

M.M. El‐MoftyDepartment of Zoology, Faculty of Science , Alexandria University , Alexandria, EgyptI.A. SadekDepartment of Zoology, Faculty of Science , Alexandria University , Alexandria, EgyptAfaf SolimanDepartment of Pathology, Faculty of Medicine , Alexandria University , Alexandria, EgyptAhmad Magdy MohamedZoology Department, Faculty of Science , Mounofia University , Shebin El Kom, EgyptSaber SakreZoology Department, Faculty of Science , Mounofia University , Shebin El Kom, Egypt
1987en
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Neoplastic lesions were induced in 10 out of 58 experimental toads (Bufo regularis) force-fed with alpha-ecdysone, which naturally occurs in the leaves of bracken fern (Pteris aquilina). The results of this study prove that alpha-ecdysone may be one of the factors responsible for the carcinogenicity of bracken fern plant fed to cattle and other experimental animals.

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