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Measuring inconsistency in meta-analyses

Julian P. T. HigginsMRC Biostatistics Unit, Institute of Public Health, Cambridge CB2 2SR. [email protected]Simon G. ThompsonMRC Biostatistics Unit, Institute of Public Health, Cambridge CB2 2SR,Jonathan J DeeksCancer Research UK/NHS Centre for Statistics in Medicine, Institute of Health Sciences, Oxford OX3 7LFDouglas G. AltmanCancer Research UK/NHS Centre for Statistics in Medicine, Institute of Health Sciences, Oxford OX3 7LF
2003en
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Cochrane Reviews have recently started including the quantity I2 to help readers assess the consistency of the results of studies in meta-analyses. What does this new quantity mean, and why is assessment of heterogeneity so important to clinical practice?

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