High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells
Yanfang Fu1] Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, Massachusetts, USA. [2] Center for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts, USA. [3] Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, Massachusetts, USA. [4] Department of Pathology, Harvard Medical School, Boston, Massachusetts, USAJennifer A FodenCenter for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts, USACyd KhayterCenter for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts, USAMorgan L. MaederCenter for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts, USADeepak ReyonCenter for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts, USAJ. Keith JoungCenter for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts, USAJeffry D. SanderCenter for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts, USA
2013en
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