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A 44Ti/44Sc radionuclide generator for potential application of 44Sc-based PET-radiopharmaceuticals

D. V. Filosofov Joint Institute of Nuclear Research, Laboratory of Nuclear Problems, Dubna, Russische FöderationNatalia S. Loktionova University of Mainz, Institute of Nuclear Chemistry, MainzFrank Rösch
2010en
ABI

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44Ti/44Sc radionuclide generators are of interest for molecular imaging. The 3.97 h half-life of 44Sc and its high positron branching of 94% may stimulate the application of 44Sc labelled PET radiopharmaceuticals. However, both 44Ti production and 44Ti/44Sc generator design represent challenges for basic radiochemistry.

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