Maqola

Surface-Textured Mixed-Metal-Oxide Nanocrystals as Efficient Catalysts for ROS Production and Biofilm Eradication

Nitee KumariCreative Research Initiative Center for Nanospace-confined Chemical Reactions (NCCR) and Department of Chemistry, Pohang University of Science and Technology (POSTECH), Pohang 37673, KoreaSumit KumarCenter for Soft and Living Matter, Institute for Basic Science (IBS), and ▽Department of Biomedical Engineering, School of Life Sciences and ⊥Department of Chemical Engineering, School of Energy and Chemical EngineeringUlsan National Institute of Science and Technology (UNIST), Ulsan 44919, KoreaMamata KarmacharyaCenter for Soft and Living Matter, Institute for Basic Science (IBS), and ▽Department of Biomedical Engineering, School of Life Sciences and ⊥Department of Chemical Engineering, School of Energy and Chemical EngineeringUlsan National Institute of Science and Technology (UNIST), Ulsan 44919, KoreaSateesh DubbuCreative Research Initiative Center for Nanospace-confined Chemical Reactions (NCCR) and Department of Chemistry, Pohang University of Science and Technology (POSTECH), Pohang 37673, KoreaTaewan KwonCreative Research Initiative Center for Nanospace-confined Chemical Reactions (NCCR) and Department of Chemistry, Pohang University of Science and Technology (POSTECH), Pohang 37673, KoreaVarsha SinghAdvanced Analysis Center, Korea Institute of Science and Technology, Seoul 02792, KoreaKeun Hwa ChaeAdvanced Analysis Center, Korea Institute of Science and Technology, Seoul 02792, KoreaAmit KumarCreative Research Initiative Center for Nanospace-confined Chemical Reactions (NCCR) and Department of Chemistry, Pohang University of Science and Technology (POSTECH), Pohang 37673, KoreaYoon‐Kyoung ChoCenter for Soft and Living Matter, Institute for Basic Science (IBS), and ▽Department of Biomedical Engineering, School of Life Sciences and ⊥Department of Chemical Engineering, School of Energy and Chemical EngineeringUlsan National Institute of Science and Technology (UNIST), Ulsan 44919, KoreaIn Su LeeCreative Research Initiative Center for Nanospace-confined Chemical Reactions (NCCR) and Department of Chemistry, Pohang University of Science and Technology (POSTECH), Pohang 37673, Korea

2020en

ABI

Annotatsiya

Next-generation catalysts are urgently needed to tackle the global challenge of antimicrobial resistance. Existing antimicrobials cannot function in the complex and stressful chemical conditions found in biofilms, and as a result, they are unable to infiltrate, diffuse into, and eradicate the biofilm and its associated matrix. Here, we introduce mixed-FeCo-oxide-based surface-textured nanostructures (MTex) as highly efficient magneto-catalytic platforms. These systems can produce defensive ROS over a broad pH range and can effectively diffuse into the biofilm and kill the embedded bacteria. Because the nanostructures are magnetic, biofilm debris can be scraped out of the microchannels. The key antifouling efficacy of MTex originates from the unique surface topography that resembles that of a ploughed field. These are captured as stable textured intermediates during the oxidative annealing and solid-state conversion of β-FeOOH nanocrystals. These nanoscale surfaces will advance progress toward developing a broad array of new enzyme-like properties at the nanobio interface.

Hali tarjima qilinmagan

Identifikatorlar

DOI: 10.1021/acs.nanolett.0c03639

Iqtiboslar va manbalar

2 ta iqtibos0 ta foydalanilgan manba

Koʻrsatkichlar — AkademScholar