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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings 1PII of original article: S0169-409X(96)00423-1. The article was originally published in Advanced Drug Delivery Reviews 23 (1997) 3–25. 1

Christopher A. LipinskiCentral Research Division, Pfizer Inc., Groton, CT 06340, USA. [email protected]Franco LombardoCentral Research Division, Pfizer Inc., Groton, CT 06340, USABeryl W. DominyCentral Research Division, Pfizer Inc., Groton, CT 06340, USAPaul J. FeeneyCentral Research Division, Pfizer Inc., Groton, CT 06340, USA
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