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Synergistic effect of ZnO nanoparticles and hesperidin on the antibacterial properties of chitosan

İbrahi̇m ErolDepartment of Chemistry, Faculty of Science and Arts, Afyon Kocatepe University, Afyonkarahisar, TurkeyÖmer HazmanDepartment of Chemistry, Faculty of Science and Arts, Afyon Kocatepe University, Afyonkarahisar, TurkeyMecit AksuDepartment of Chemistry, Faculty of Science and Arts, Düzce University, Düzce, TurkeyEmine BulutDepartment of Food Processing, Bolvadin Vocational School, Afyon Kocatepe University, Afyonkarahisar, Turkey
2022en
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was 18.3, the same value increased to 22.3 for the composite containing 6 wt% the ZnO-HSP. The HSP increased the antioxidant capacity of both the ZnO-HSP particles and the CS/ZnO-HSP nanocomposites, reducing the toxic effects of ZnO nanoparticles. Thus, it was determined that the CS/ZnO-HSP nanocomposites did not have any cytotoxicity in healthy human cells. The fact that the produced nanocomposites exhibit antibacterial activity and do not harm human cells shows that they can be a safe product for health. From all these results, this triple hybrid system is hoped that it will be used in biomedical applications as a naturally-sourced, environmentally friendly, and cost-effective composite biomaterial by combining its antimicrobial and strong antioxidant properties.

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