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Processing methods for making porous bioactive glass‐based scaffolds—A state‐of‐the‐art review

Francesco BainoDepartment of Applied Science and Technology, Institute of Materials Physics and Engineering Politecnico di Torino Torino ItalyElisa FiumeDepartment of Applied Science and Technology, Institute of Materials Physics and Engineering Politecnico di Torino Torino ItalyJacopo BarberiDepartment of Applied Science and Technology, Institute of Materials Physics and Engineering Politecnico di Torino Torino ItalySaeid KargozarDepartment of Anatomy and Cell Biology, Tissue Engineering Research Group (TERG), School of Medicine Mashhad University of Medical Sciences Mashhad IranJuliana MarchiCenter for Natural Sciences and Humanities Federal University do ABC Santo André BrazilJonathan MasseraFaculty of Medicine and Health Technology Tampere University Tampere FinlandEnrica VernéDepartment of Applied Science and Technology, Institute of Materials Physics and Engineering Politecnico di Torino Torino Italy

2019en

ABI

Annotatsiya

Abstract Bioactive glasses exhibit the unique ability of bone bonding, thus creating a stable interface by stimulating bone cells toward mechanisms of regeneration and self‐repair activated by ionic dissolution products. Therefore, 3D glass‐derived scaffolds can be considered ideal porous templates to be used in bone tissue engineering strategies and regenerative medicine. This review provides a comprehensive overview of all technological aspects relevant to the fabrication of bioactive glass scaffolds, including the fundamentals of materials processing, a summary of the conventional porogen, and template‐based methods and of recent additive manufacturing technologies, which are promising for large‐scale production of highly reproducible and reliable implants suitable for a wide range of clinical applications.

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Identifikatorlar

DOI: 10.1111/ijac.13195

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